新型血管吻合用支架溶解性能比较性研究  

Comparative study on the dissolutionrate of a new stent

作　　者：梁向党[1] 张伯勋[1] 范昱玮[2] 王岩[1] 

机构地区：[1]解放军总医院,北京市100853 [2]清华大学材料系,北京市100084

出　　处：《医疗卫生装备》2003年第7期5-6,共2页Chinese Medical Equipment Journal

基　　金：国家自然科学基金资助(编号为30100186)。

摘　　要：目的:研制一种可溶性血管内支架辅助血管断端吻合,并检测该支架在血管吻合过程中的溶解性能。方法:选用高纯度低分子量明胶为主要原料制备血管吻合用支架,利用该支架进行血管吻合操作,观察支架在体内和体外的溶解性能,并从超微结构方面进行研究。结果:明胶类可溶性血管内支架在体内、体外均具有较快的溶解速度,与同类支架相比具有明显的优势。结论:明胶类可溶性血管内支架具有速溶的特性,适合于进行血管吻合操作。A new soluble intravascular stent made of gelatin,a supplementary instrument of anastomosis,is devel-oped,and its dissolution rates in vascular anastomosis and the test in vitro are investigated.The high-purity and low-molecular-weight gelation is dissolved in a hot water bath,and both inorganic salts and blowing agent are mixed together,then the stent is made by spinning machine.Used to anastomose rabbit femoral arteries,the stent is studied from the angle of ultrastructure.Compared with other stents,the stent dissolves quickly so that it is suitable for vas-cular anastomosis.

关 键 词：血管内支架 血管吻合 溶解性能 明胶 超微结构 

分 类 号：R318.08[医药卫生—生物医学工程]