不育油漆工精子连接段异常的超微病理检查  

An Electron Microscope Observation for the Abnormal Ultrastructure of the Connecting Piece in Human Spermatozoa from Infertile Painters

作　　者：王刚[1] 刘子龙[1] 胡艳群[1] 熊忠明[1] 肖慧珠[1] 熊承良[1] 

机构地区：[1]华中科技大学同济医学院生殖医学中心,湖北武汉430030

出　　处：《中华男科学杂志》2003年第4期282-285,共4页National Journal of Andrology

摘　　要：目的 :应用透射电镜技术 ,对油漆工不育病人的精子连接段进行病理检查。　方法 :8例不育油漆工 ,年龄2 1～ 32岁 ,精子标本常规电镜制片 ,透射电镜观察。　结果 :精子连接段异常可分 6类 ,以连接段异常伴真性核软化最为严重。　结论 :油漆工不育病人精子连接段异常可能与核基因组与线粒体基因组表达障碍及精子分化阶段细胞信号转导异常有关。Objectives: To investigate possible abnormalities of the sperm neck in eight infertile painters observed by transmission electron microscope. Methods: Spermatozoa from 8 infertile painters (21～32 years old) were observed by transmission electron microscope. Results: The abnormalities of the connecting piece could be divided into 6 types, among which the anomaly of the connecting piece concomitant with a true nuclemalamic condition was the most serious. Conclusions: The abnormalities may be related to expression obstacles of nuclear genome and mitochondrial genome, and to anomalous cellular signal transduction during spermiogenesis as well.

关 键 词：不育 油漆工 精子 超微结构 病理检查 

分 类 号：R698.2[医药卫生—泌尿科学] R135.1[医药卫生—外科学]