γ—苯丙基丙二酸的合成及其表征  

Synthesis and Indication of(γ-phenylpropyl) malonic Acid

作　　者：张贵昌 马克荣[2] 孙继昌[2] 李冬梅[2] 王雅民[2] 

机构地区：[1]辽阳石油化工专科学校 [2]辽宁大学化学系

出　　处：《辽宁大学学报（自然科学版）》1992年第2期73-78,共6页Journal of Liaoning University：Natural Sciences Edition

摘　　要：邻菲罗啉和丙二酸型络合剂形成的双配体络合物,无论对络合物进行理论研究还是开发利用都具有广泛的应用前景,为填补市场紧缺,满足科研急需,我们参阅有关文献自行设计了由3-苯基-1-丙醇开始,经3-苯丙基氯,再与丙二酸二乙酯的碳负离子进行亲核取代,继而水解合成苯丙基丙二酸的合成路线,合成了r-苯丙基丙二酸。The synthesis of (γ-phenylpropyl)-malonic acid is reported in this paper. The compound is a diligand complex reagent of Ophenanthroline and malonic acid model. According to our synthetic procedure the 3-phenylpropyl chloride was obstained from beginning reagent 3-phenylpropyl alcohol. On carrying out a nucleophilic substitution on diethyl malonate, γ-phenylpropyl malonic acid was finally got by hydrolyzed diethyl malonate.

关 键 词：苯丙基氯 丙二酸二乙酯 亲核取代 

分 类 号：O623.613[理学—有机化学]