小剂量辛伐他汀治疗急性冠状动脉综合征的探讨  

Curative Discussion on Acute Coronary Syndrome Treated with Small Dose of Simvastatin

作　　者：向群[1] 姚强[1] 阮力[1] 李国军[1] 蒋兰晔[1] 

机构地区：[1]湖南省怀化铁路总公司医院内二科,湖南怀化418000

出　　处：《黑龙江医学》2003年第8期575-577,共3页Heilongjiang Medical Journal

摘　　要：目的　探讨调脂药辛伐他汀对急性冠状动脉综合征的疗效。方法　于治疗前后严密监测血脂指标 ,在常规基础治疗的前提下 ,观察 30例急性冠状动脉综合征给予辛伐他汀 1 0mg ,睡前顿服 ,连用 1 2周为 1个疗程。分析临床症状、体征、心电图及血脂变化。结果　血脂改善显著 ,血管事件 1 0 34% ,较对照组 33%明显降低。结论　辛伐他汀主要通过有效的调脂效应 ,对急性冠状动脉综合征疗效显著。是值得临床选择的药物。Objective To discuss the curative effect of simvastatin for acute coronary syndrome (ACS). Methods The 10mg of simvastatin was given to 30 cases ACS patient for a course of 12 weeks based on routine treatment. The clinical manifestations, ECG and blood lipid were analyzed. Results The blood lipid was decreased and improved obviously with blood vessel disease 10.34% than that in control group of 32%. Conclusion This drug had obvious efficacy on ACS with adjusted effect. It should be selected in clinic.

关 键 词：内科学 小剂量 辛伐他汀 急性冠状动脉综合征 疗效 血脂指标 

分 类 号：R541.4[医药卫生—心血管疾病]