包疮叶的化学成分研究(英文)  

Chemical Constituents of Maesa indica

作　　者：来国防[1] 王易芬[1] 曹建新[1] 罗士德[1] 

机构地区：[1]中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,昆明650204

出　　处：《中国天然药物》2003年第2期76-78,共3页

摘　　要：目的 :研究包疮叶的化学成分。方法 :采用硅胶柱层析法进行分离 ,根据光谱数据鉴定结构。结果 :从中分得 6个化合物 ,分别为 :2 2 O (2 methylbutyryl) 2 8 al 1 2 en olean 3β ,1 6α diol(1 ) ,2 2 O hexanoyl 2 8 al 1 2 en olean 3β ,1 6α diol(2 ) ,1 ,1 2 bis(3,3′ dihydroxy 4 ,4′ dimethyl 5 ,5′ dimethoxyphenyl)dodecane(3) ],3β ,1 6α ,2 2α ,2 8β tetrahydroxy 1 3β ,2 8 epoxy olean(4 ) ,(2 4R) stigmast 7,2 2 (E) dien 3α ol(5 ) ,(2 4R) stigmast 7,2 2 (E) dien 3β D glucopyranoside(6 )。 结论 :化合物 1为一新的齐墩果烷型甙元 ,其它AIM:To study the chemical constituents of Maesa. indica. METHOD:Compounds were separated by column chromatography on silica gel, Sephadex LH 20 and their structures were elucidated based on the spectral analyses including 1D NMR( 1 HNMR, 13 CNMR) and 2D NMR(COSY, HMQC, HMBC). RESULT:Two triterpenoids aglycone and other four compounds were isolated from M. indica and identified as 22 O (2 methylbutyryl) 28 al 12 en olean 3β,16α diol(1), 22 O hexanoyl 28 al 12 en olean 3β,16α diol(2), 1,12 bis(3,3′ dihydroxy 4, 4′ dimethyl 5, 5′ dimethoxyphenyl) dodecane(3)], 3β,16α, 22α, 28β tetrahydroxy 13β, 28 epoxy olean(, 3β,16α, 22α, 28β tetrahydroxy 13β, 28 epoxy olean(4),(24 R ) stigmast 7, 22( E ) dien 3α ol(5),(24 R ) stigmast 7, 22( E ) dien 3β D glucopyranoside(6). CONCLUSIONS:Compound 1 was a new compound,and other compounds were obtained from M. indica for the first time.

关 键 词：包疮叶 化学成分 研究 硅胶柱层析法 

分 类 号：R284.1[医药卫生—中药学]