855名正常人15群钩体血清抗体测定及聚类分析  

Cluster analysis and determination of antibodies against 15 leptospira populations in 855 healthy persons

作　　者：郭绶衡[1] 吴子贵[1] 李伟[1] 

机构地区：[1]湖南省疾病预防控制中心,长沙市410005

出　　处：《中国热带医学》2003年第5期597-599,共3页China Tropical Medicine

摘　　要：目的　探讨钩体疫区未接种菌苗人群钩体抗体情况及其类别。　方法　按国标用 15群 15型标准钩体菌株测抗体 (MTA法 ) ,用美国SPSSV10 .0forWindows统计软件进行抗体滴度聚类分析。　结果　黄疸出血群抗体阳性率最高 ( 3 0 .64 % ) ,拜伦群次之 ( 2 0 .82 % ) ,曼耗群、巴达维亚群和塔拉索夫群阳性率极低 ;人群抗体可分为三类。　结论　聚类分析法应用于人群钩体抗体分析作为一种分析方法或思路 ,具有一定的理论意义和实际应用意义。Objective To explore the level of antibody against leptospira and its types in populations without immunization of leptospira vaccine in leptospirosis endemic areas in Hunan Province. Methods Antibody levels were determined using standard 15 types of leptospira antigens belong to 15 leptospira populations (MTA Method). The cluster analysis of antibody titres were performed using SPSS10.0 software for windows. Results The antibody positive rate of icterohemorrhagic group was the highest (30.64%) , next was Balllum (20.82%), while the antibody positive rates in the groups of Manhao, Bataviae and Tarassovi were the lowest. Conclusion The application of cluster analysis in the analyzing the level of antibody against leptospira in the human population possesses certain theoretic and practical significance.

关 键 词：血清抗体 测定 聚类分析 钩端螺旋体 

分 类 号：R377.5[医药卫生—病原生物学] R446.5[医药卫生—基础医学]