双氯芬酸栓治疗前列腺切除术后膀胱痉挛  

Diclofenac suppository in treatment of cystospasm post-prostatectomy

作　　者：刘加升[1] 王义兆 马元华[1] 张雷[1] 

机构地区：[1]沛县中医院外科,江苏沛县221600 [2]江宁区医院外科,江苏南京211100

出　　处：《中国新药与临床杂志》2003年第8期459-461,共3页Chinese Journal of New Drugs and Clinical Remedies

摘　　要：目的 :比较双氯芬酸栓与山莨菪碱 (aniso damine)注射液对前列腺切除术后膀胱痉挛的治疗效果。方法 :64例膀胱痉挛病人 ,年龄 ( 68±s10 )a ,分为双氯芬酸栓组 (双氯芬酸栓 5 0mg ,直肠给药 ,q12h)和山莨菪碱组 (山莨菪碱 10mg ,im ,q 12h)各32例。 2组各用药 2d ,再交换用药 2d。观察 2组疗效和不良反应。结果 :d 1～ 2双氯芬酸组和山莨菪碱组总有效率为 88%和 5 9%(P <0 .0 1) ,d 3～4 ,2组总有效率为 91%和 72 %,2组相比差异有显著意义 ,P <0 .0 5。结论 :双氯芬酸栓治疗前列腺切除术后膀胱痉挛疗效满意 ,优于肌内注射山莨菪碱。AIM:To compare the clinical efficacy of diclofenac suppository and injection anisodamine in the treatment of cystospasm post-prostatectomy. METHODS: Sixty-four patients (age (68±s10)a) with cystospasm were divided into two groups: diclofenac suppository (50 mg, rectal medication, q 12 h) and anisodamine (10 mg, im, q 12 h) groups. Thirty-two patients received diclofenac suppository in the d 1-2 and anisodamine in the d 3-4, while thirty-two patients received anisodamine in the d 1-2 and diclofenac suppository in the d 3-4. RESULTS:In the d 1-2, the total effective rate was 88 % and 59 %(P< 0.01), in two grups. In the d 3-4, the total effective rate was 91 % and 72 %, respectively. There was different between two groups (P<0.05). CONCLUSION:The efficacy of diclofenac suppository in treating cystospasm post-prostatectomy is satisfactory and superior to injection anisodamine.

关 键 词：前列腺切除术 术后 膀胱痉挛 双氯芬酸栓 山莨菪碱 

分 类 号：R983[医药卫生—药品] R694[医药卫生—药学]