山东省恙虫病调查  

Investigation on scrub typhus in Shandong province

作　　者：李忠[1] 孙桐[1] 王勤忠[1] 王显军[1] 丁淑军[1] 冯开军[1] 崔嵩[1] 胡滨[1] 

机构地区：[1]山东省疾病预防控制中心传染病防治所,济南250014

出　　处：《中国公共卫生》2003年第8期966-967,共2页Chinese Journal of Public Health

基　　金：山东省卫生厅青年科技基金资助项目 (970 1 )

摘　　要：目的　了解山东省恙虫病流行特点。方法　采用PCR技术及血清学等方法对山东地区人间和鼠间恙虫病感染情况进行流行病学调查。结果　首次在黄河以北地区检出恙虫病感染鼠 ,感染率高达 15 6 3% (PCR结果 ) ;从褐家鼠中检出恙虫病立克次体 ,血清学显示其感染率达 10 % ;通过血清学检查还从大仓鼠中检出恙虫病立克次体抗体 ,其感染率达 15 6 3%。除已证实的疫区外 ,还证实山东省潍坊、东营和菏泽 3市存在恙虫病人间或鼠间感染。结论　山东省广泛存在恙虫病疫区 ,黑线姬鼠为主要传染源 ,其血清学阳性率达 19 4 6 % ,褐家鼠以及大仓鼠也有可能是本病的重要传染源。Objective To learn the epidemic status of scrub typhus in Shandong province. Methods Systemic survey was carried out in different regions in Shandong province by PCR and serological tests. Results By PCR positive rats were found in the region north to Yellow River for the frist time in the province and the positive rate was 15.63%.Serological investigation showed that the positive rates of R.norvegicus and C.triton were 10% and 15.63% respectively.Weifang,Dongying and Heze were confirmed to be the epidemic area of scrub typhus in the province for the first time. Conclusion Scrub typhus was epidemic extensively in the province.The major infetion source of infection was A.agrarius.Its serological positive rate was 19.46%;but R.norvegicus agrarlus and C triton maybe other important source of infection.

关 键 词：山东 恙虫病 PCR技术 褐家鼠 

分 类 号：R376.2[医药卫生—病原生物学]