ATP对室上性心动过速患者窦房结和房室结功能的影响  

Effect of ATP on the functions of sino-atrial node and atrioventricular node of patients with the supraventricular tachycardia

作　　者：邹路云[1] 冯国珍[1] 刘仁光[1] 

机构地区：[1]锦州医学院附属医院,研究生121001

出　　处：《临床心电学杂志》1992年第3期104-106,共3页Journal of Clinical Electrocardiology

摘　　要：对30例室上速患者用食管心房调搏诱发SVT110例次,观察不同剂量的ATP(10mg、20mg、30mg)在终止SVT过程中对窦房结和房室结功能的影响。发现ATP对窦房结和房室结有负性变率和负性传导作用,且随ATP用量的增加而加重。以ATP治疗室上速有一定风险,不宜作为首选药物。110 episodes of supraventricular tachycardia(SVT)were induced by esophago—atrial pacing in 30 patients with SVT(11 patients with atrioventricular nodal reentrant tachycardia, 19 patients with atrioventricular reentrant tachycardia). By using different doses(10mg, 20mg, 30mg)of ATP for the termination of SVT, we observed in the meantime its effects on the functions of sino-atriral node (SAN) and atrio-ventricular node(AVN). The result showed that ATP had a strong negative chronotropic and dromotropic effect on the SAN and AVN during the termination of SVT. Also with increasing the doses, the stronger the effects were observed. Because the treatment for SVT with ATP may appear a variety of complications and crisis, so it is not desirable to use ATP as a first-choiced drug.

关 键 词：三磷酸腺苷 电生理学 心动过速 

分 类 号：R541.710.5[医药卫生—心血管疾病]