肌肽与细胞线粒体抗氧化作用的比较  

Comparison of anti-oxidation effect between carnosine and mitochondria

作　　者：杨歌德[1] 周宏博[1] 姜玉梅[1] 

机构地区：[1]哈尔滨医科大学生物化学教研室,黑龙江哈尔滨150086

出　　处：《哈尔滨医科大学学报》2003年第4期355-356,358,共3页Journal of Harbin Medical University

摘　　要：目的　了解肌肽抗氧化作用的效果。方法　通过单位时间内邻苯三酚自氧化率的变化 ,进行肌肽与线粒体抗氧化作用的比较。结果　线粒体对邻苯三酚自氧化抑制率为 1.2 % μg (pro·min) ,肌肽对邻苯三酚自氧化抑制率为 5 5 .1%mmol (L·min)。结论　肌肽对细胞的氧化损伤有良好保护作用。Objective To study the anti oxidation effect of carnosine.Methods The anti oxidation effects of carnosine and mitochondria were measured by the value of self oxidation ratio of pyrogallol per minute.Results The inhibition rate of mitochondria for self oxidation of pyrogallol was 1.2%μg/(pr·min),and the inhibition rate of carnosine for self oxidation of pyrogallol was 55.1%mmol/(L·min).Conclusion Carnosine can protect cells from oxidative damage.

关 键 词：肌肽 细胞线粒体 抗氧化作用 比较 邻苯三酚 自由基 

分 类 号：Q503[生物学—生物化学]