维吾尔族冠心病患者血脂与冠状动脉狭窄的关系  

The relationship between levels of serum lipids,apolipoprotein A and B and extent of coronary stenosis and judgement of extent of coronary stenosis in 60 uygur nationality

作　　者：匡政宇[1] 洪秀芳[1] 杨坤河[1] 张向阳[1] 黄定[1] 王炎[1] 田文庆[1] 艾尔肯.阿吉 

机构地区：[1]新疆医科大学第一附属医院心内科,新疆乌鲁木齐830054

出　　处：《新疆医科大学学报》2003年第4期346-347,共2页Journal of Xinjiang Medical University

基　　金：新疆医科大学第一附属医院硕士启动基金(编号 :98-YFYY-16)

摘　　要：目的:探讨脂代谢各项指标在维吾尔族冠心病诊断中的价值及冠脉狭窄程度的预测。方法:经选择性冠状动脉造影确定维吾尔族冠心病患者 30例及同族别正常者 30例 ,测定其冠脉狭窄程度及血清总胆固醇 ( TC)、甘油三酯 ( TG)、高密度脂蛋白 ( HDL )、低密度脂蛋白 ( L DL )、载脂蛋白 A( Apo A)及载脂蛋白 B( Apo B) ;采用相关分析及判别分析进行统计学处理。 结果 :维吾尔族患者 TC、TG、L DL、Apo B水平高于对照组 ,冠脉狭窄与 TC、L DL、Apo B呈正相关 ,与 HDL成负相关 ,Apo B水平对判别作用最大 ,其次为 HDL及 L DL。 结论 :血清 Apo B、L DL 可作为冠心病的诊断指标 。Objective: The purpose of this paper is to observe the relationship between extent of coronary stenosis and levels of serum lipids , Apolipoprotein A and B and distinguish extent of coronary stenosis in Uygur nationality. Methods: 30 Uygur cases were patient group because the extent of coronary stenosis was ≥50% by selected coronary angiography. Other 30 paients were control group because of the extent being less than 50%. All patients were measured on the levels of total cholesterol (TC)、 triglyceride (TG)、 high density lipoprotein (HDL)、 low density lipoprotein (LDL)、 apolepoprotein A and lipoprotein B (ApoA. ApoB). Results: The levels of TC、 TG、 LDL、ApoB of patient group were higer than that of control group. Levels of HDL were decreased. The levels of TC、 LDL、 ApoB had significant positive correlation and HDL levels had negative correlation. The levels of ApoB were the biggest contribution to confirm the severity of coronary stenosis in Uygur nationality. Conclusions: ApoB and HDL are the indication in predicting extent of coronary stenosis in Uygur nationality

关 键 词：维吾尔族 冠脉狭窄 血脂 载脂蛋白 判别分析 

分 类 号：R541.4[医药卫生—心血管疾病]