双歧异黄酮奶粉对化疗荷瘤小鼠减毒增效作用的研究  

STUDIES OF REDUCING POISON AND INCREASING EFFECT OF BIFIDUS ISOFLAVONE MILK POWER ON IMMUNE FUNCTION OF TUMOR-BEARING MICE AFTER CHEMIOTHERAPY

作　　者：刘伯阳[1] 苏富琴[1] 刘吉成[1] 

机构地区：[1]齐齐哈尔医学院医药科学研究所,黑龙江齐齐哈尔161042

出　　处：《中国微生态学杂志》2003年第4期214-215,共2页Chinese Journal of Microecology

摘　　要：目的 :研究双歧异黄酮奶粉对化疗后荷瘤小鼠免疫功能的影响。方法 :以S180 荷瘤C57BL/6小鼠为模型 ,系统地研究双歧异黄酮奶粉对瘤重和细胞功能的影响。结果 :双歧异黄酮奶粉对荷瘤鼠化疗所引起的免疫功能低下具有明显的恢复作用 ,可显著提高化疗荷瘤鼠T细胞转化能力 ,明显促进化疗荷瘤鼠白介素 2 (IL 2 )分泌水平。结论 ;双歧异黄酮奶粉能够拮抗肿瘤抗原和化疗所引起的免疫抑制。Objective:To research the effect of Bifidus isoflavone milk power on immune function of Tumor-bearing mice.Methods:S 180 bearing C 57 BL/6 mice as model,investigate effects of Bifidus isoflavone milk power on tumor weight and immunological function of spleen cells systematically.Results:Bifidus isoflavone milk power can obviously restore immune function of Tumor-bearing mice reduced by chemiotherapy,promote proliferation of activated T cell and interleukin-2(IL-2) levels of Tumor-bearing mice.Conclusion:Bifidus isoflavone milk power can reverse the immunological inhibition caused by tumor antigen and chemiotherapy.

关 键 词：双歧异黄酮奶粉 化疗 荷瘤小鼠 减毒增效作用 白介素-52 

分 类 号：R37[医药卫生—病原生物学] R730[医药卫生—基础医学]