大鼠胰岛内γ-干扰素样免疫反应阳性物质的表达  

Expression of IFN-γ-like immunoreactive positive substances in the rat pancreas islet

作　　者：胡格[1] 穆祥[1] 陈树林[2] 欧阳五庆[2] 李育良[2] 

机构地区：[1]北京农学院动物科学系,北京102206 [2]西北农林科技大学畜牧兽医学院,陕西杨陵712100

出　　处：《动物学报》2003年第4期540-542,共3页ACTA ZOOLOGICA SINICA

基　　金：国家自然科学基金 (No .3 9770 5 77)资助~~

摘　　要：In order to study the correlation between the neuroendocrine and immune systems, we observed the distribution and expression of interferon γ(IFN-γ) in cells of SD rat pancreas islets using the streptavidin-perosidase immunohistochemical method. A number of IFN-γ-like positive substances were found in the in the cytoplasm of pancreas islet A cells, but the nucleus could not be stained. Most of the IFN-γ-like positive cells were distributed around the periphery of the pancreas islet, the cells were round or oval in shape and the cell body was relatively large. Results suggest IFN-γ may play a role in the regulation of the function of pancreas islet cells and act as a neuro-immune medium .In order to study the correlation between the neuroendocrine and immune systems, we observed the distribution and expression of interferon γ(IFN-γ) in cells of SD rat pancreas islets using the streptavidin-perosidase immunohistochemical method. A number of IFN-γ-like positive substances were found in the in the cytoplasm of pancreas islet A cells, but the nucleus could not be stained. Most of the IFN-γ-like positive cells were distributed around the periphery of the pancreas islet, the cells were round or oval in shape and the cell body was relatively large. Results suggest IFN-γ may play a role in the regulation of the function of pancreas islet cells and act as a neuro-immune medium .

关 键 词：大鼠 胰岛 Γ-干扰素 免疫反应阳性物质 表达 神经免疫调节 

分 类 号：Q57[生物学—生物化学]