丙二酸亚异丙酯的单取代Mannich碱的制备  

The Preparation of Single Substitution Mannich Bases of Isopropylidene Malonate

作　　者：黄少云[1] 王福来[2] 

机构地区：[1]武汉化工学院制药系,湖北武汉430074 [2]武汉大学化学系,湖北武汉430072

出　　处：《湖北化工》2003年第4期16-17,共2页Hubei Chemical Industry

摘　　要：研究了丙二酸亚异丙酯与苯甲醛、脂肪族胺的单取代曼尼希反应,通过对曼尼希碱的IR、NMR及元素分析表征了其结构,反应遵循Hellmman规律,生成的曼尼希碱主要以内盐式存在。Mannich reaction was carried out between isopropylidene malonate, benzaldehyde and an aliphatic amines. The structure of Mannich bases were confirmed by elemental analysis, IR, NMR and UV speetrosco- pies. The Mannich reaction follow Hellmman rule.

关 键 词：丙二酸亚异丙酯 单取代 MANNICH碱 制备 苯甲醛 脂肪族胺 曼尼希反应 

分 类 号：O623.624.2[理学—有机化学]