刺五加治疗急性脑梗死血液流变学变化的临床研究  

Clinical investigate of Ciwujia injection and Compound salvia miltiorrhiza injection on treatment of acute cerebral infarction patients

作　　者：李玫[1] 蔡鸿[1] 刘波[1] 

机构地区：[1]贵州省人民医院神经内科,贵阳550002

出　　处：《贵州医药》2003年第8期701-702,共2页Guizhou Medical Journal

摘　　要：目的对比观察刺五加注射液与复方丹参注射液治疗急性脑梗死患者的血液流变学变化。方法 6 4例患者随机分为实验组 (n =32 ,住院期间每日静脉滴注刺五加注射液 2 5 0ml,连续1 4d)和对照组 (n =32 ,住院期间每日静脉滴注复方丹参注射液 2 5 0ml,连续 1 4d) ,分别对上述两组患者治疗前和治疗后第 7d、1 4d作全血粘度 (CP)、红细胞压积 (HCT)、红细胞聚集指数 (RCI)、血小板聚集率 (PCR)检测。结果两组患者治疗前上述参数组间比较差异无显著性意义 (P >0 .0 5 ) ;治疗后第 7d、1 4d ,两组上述参数均明显低于治疗前 (P <0 .0 5或P <0 .0 1 ) ;实验组CP、RCI和PCR明显低于对照组 (P <0 .0 5 )。结论在改善急性脑梗死患者血液流变学 ,促进脑部血液循环 ,降低死亡率等方面 。Objective To investigate the effects of Ciwujia and Compound salvia miltiorrhiza on treatment of acute cerebral infarct patients. Methods 32 patients with acute cerebral infarct were selected randomly and treated with Ciwujia injection of 250ml for intravenous drip; another 32 patients were selected as control group and treated with Compound salvia miltiorrhiza injection of 250ml for intravenous drip. The treatment for both groups was a fourteen-day course of one dose a day. All of patients were tested for hemorrheology parameters. Results There was no obvious difference of changes in hemorrheology parameters on treatment before, but it was obvious difference on the seventh day and the fourteenth day between the both groups( P <0.05).Conclusion Ciwujia injection has a good and safe therapeatic effect on treating acute cerebral infarction than Compound salvia miltiorrhiza injection.

关 键 词：急性脑梗死 刺五加注射液 复方丹参注射液 中药制剂 血液流变学 

分 类 号：R277.733.3[医药卫生—中医学]