天鹅记忆接骨器治疗兔肱骨干骨折  

Swan-shaped bone fixation device made of Ni-Ti shape memory alloy for treating humeral fracture in rabbits

作　　者：康庆林[1] 张春才[1] 高堂成[1] 许硕贵[1] 任可[1] 

机构地区：[1]第二军医大学长海医院骨科,上海20043

出　　处：《第一军医大学学报》2003年第7期728-730,共3页Journal of First Military Medical University

摘　　要：目的观察天鹅记忆接骨器(SMC)治疗动物肱骨干骨折的疗效。方法选用新西兰大白兔30只建立肱骨干骨折模型,一侧用SMC固定,对侧以4孔动力加压接骨板(DCP)作为对照。术后2、4、8、12周拍片观察骨愈合情况。结果术后动物全部成活,前肢负重明显少于后肢。SMC侧骨折端直接由板层骨替代连接,既不出现外骨痂,也无板下皮质骨疏松,对照侧骨折愈合速度慢,且部分骨断端有骨痂生成,所有骨干局部出现骨质疏松。结论兔肱骨干的生物力学特性和解剖形态与人肱骨干非常接近,其骨折内固定模型是研究SMC促进骨折愈合的机制的理想实验工具。Objective To establish the animal model for treating humeral fracture with swan-shaped bone fixation device made of Ni-Ti shape memory alloy. Methods Models of humeral fractures was established in 30 rabbits and on one side the fracture was fixed with the Ni-Ti shape memory alloy device (SMC side) and on the other with 4-hole dynamic compression plate (DCP side). Anteroposterior radiograph of both humeri were taken at the time points of 2, 4, 8, and 12 weeks respective-ly after operation. Results All the rabbits survived the experiment and their forelimbs bore obviously less weight than hindlimb. In SMC side, the humeral fracture healed without either osteoporosis or external callus. The fracture healing in DCP side gave rise to obvious external callus formation, and the healing process took significantly longer time than in SMC group. Conclusion The humerus of rabbit is similar to human humerus in view of their anatomic morphology and biomechanical properties, therefore rabbit humeral fracture models can be ideal for exploring the mechanism of fracture healing induced by the alloy device.

关 键 词：肱骨干骨折 天鹅记忆接骨器 治疗 兔 疗效 骨折固定术 

分 类 号：R683.41[医药卫生—骨科学]