全自动换血治疗G-6-PD缺陷症并发急性溶血的疗效观察  

Automatic exchange transfusion in newborns with acute hemolysis due to glucose-6-phosphate dehydrogenase deficiency

作　　者：邝文英[1] 郑丽萍[1] 汪伟山[1] 黄辉文[1] 

机构地区：[1]广东省珠海市妇幼保健院新生儿科,广东珠海519001

出　　处：《广东医学院学报》2003年第5期446-448,共3页Journal of Guangdong Medical College

摘　　要：目的 :观察全自动换血治疗危重G 6 PD缺陷症并发急性溶血的疗效。方法 :对 1 0例危重G 6 PD缺陷症并发急性溶血采用全自动换血治疗。结果 :总胆红素由换血前 (5 33.1 4± 1 1 5 .6 5 ) μmol/L下降至换血后 (2 95 .5 0± 88.5 1 )μmol/L ,换出率是 4 4 .5 7% ,血红蛋白增加 34.1 2 % ,红细胞增加 4 3.30 % ,换血过程无明显不良反应。结论 :全自动换血是抢救危重G 6 PD缺陷症并发急性溶血的简单、实用、安全。Objective:To assess the role of automatic exchange transfusion in glucose 6 phosphate dehydrogenase(G6PD)deficiency with acute hemolysis.Methods:Automatic exchange transfusion was used to treat 10 G6PD deficient newborns with acute hemolysis.Results:Bilirubin level was lowered from 533.14±115.65 μmol/L to 295.50±88.51 μmol/L,and its removal rate was 44.57%.Hemoglobin content and red blood cells were raised by 34.12% and 43.3% respectively.Severe adverse effects did not occur in all cases.Conclusion:Automatic exchange transfusion may be a simple,feasible,safe and effective method for treating G6PD deficient newborns with acute hemolysis.

关 键 词：换血 G-6-PD缺陷 溶血 

分 类 号：R725.5[医药卫生—儿科]