对HIV流行地区人群抗庚型肝炎病毒抗体的调查  

A survey of hepatitis G virus in a HIV endemic region.

作　　者：骆嘉拉[1] 桂希恩[1] 庄柯[1] 

机构地区：[1]武汉大学中南医院,湖北武汉430071

出　　处：《中国艾滋病性病》2003年第4期199-201,共3页Chinese Journal of Aids & STD

摘　　要：目的　在艾滋病病毒 (HIV)流行地区调查庚型肝炎 (庚肝 )病毒 (HGV)的感染率 ,并探讨其对HIV /AIDS患者病情进展的影响。方法　对某HIV流行地区 647名村民询问病史 ,检测血清抗 HGV和抗 HIV。结果　 647人中检测出抗 HGV 3 3 3例 ( 51 5% ) ,抗 HIV 3 2 8例 ( 50 7% ) ,混合感染HGV和HIV 2 10例 ( 3 2 5% ) ;其中≥ 2 0岁、有供血浆史或HIV感染者是HGV感染的高危人群。HIV感染合并HGV人群与不合并感染HGV人群相比较 ,其患AIDS或AIDS死亡者所占比例较低。结论　供血浆传播是造成该地区HGV和HIV流行的主要原因 。objective To estimate the prevalence of HGV/GBV-C in a HIV endemic re g ion and discuss the effect of HGV on HIV clinical progress. Methods ELISA was ap plied to detect HGV-Ab and HIV-Ab in villagers who were interviewed in the HIV e ndemic region. Results Out of 647 villagers, 333 (51.5%) were HGV-Ab positive, 328 (50.7%)-HIV-Ab positive and 210 (32.5%) were found to be co-infected. Th e prevalence rate of HGV infection was high in the villagers who were over 20 year s, being plasma donors and HIV-infected. However, the proportion of the co-inf ec ted patients who were ADIS or died of AIDS was comparative low. Concl usion Paid plasma donors were the main source of HGV and HIV epidemic. Co-infection with H GV can probably slow the progress of HIV/AIDS.

关 键 词：HIV 流行地区 人群 抗庚型肝炎病毒抗体 调查 艾滋病病毒 

分 类 号：R512.91[医药卫生—内科学] R512.6[医药卫生—临床医学]