乌索酸对大鼠胆汁的影响  

Effecte of Uvsolic acid on promoting bile secretion in rat

作　　者：熊筱娟[1] 陈蔚云[2] 崔江龙 李开泉[1] 陈武[1] 

机构地区：[1]江西宜春学院,江西宜春336000 [2]江西医学院,江西南昌330006 [3]宜春市第一人民医院,江西宜春336000

出　　处：《中医药学报》2003年第4期54-55,共2页Acta Chinese Medicine and Pharmacology

基　　金：国家高技术研究发展计划 (863计划 )资助项目(2 0 0 2AA2Z32 1 7)

摘　　要：目的 :观察乌索酸对动物胆汁的影响。方法 :采用麻醉大鼠行胆汁引流术 ,测定正常大鼠及APIT肝损伤大鼠的胆汁分泌量及胆汁成分 ,测定血清SB含量。结果 :ig乌索酸正常大鼠及APIT模型大鼠的胆汁流量明显增加 ,胆汁中胆红素浓度提高 ,血清胆红素含量明显降低。结论 :乌索酸有明显的利胆、促进胆红素排泄的作用。Objective: To study the bile promoting secretion of ursolic acid administrated ig in rat.Methods:Ursolic was administrated ig to the rats with liver injury induced by APIT.SB in serum were examined.The bile folw rate and theconcentration of the main components in the bile of ratsafter ig adminstration of Ursolic acid were estimated.Results:Ursolic acid administrated ig decreased the serum SB levels in the rats treated with APIT,promoted thesecretion of bile and increased the concentration ofbilirubin in the bile.Conclusion:Ursolic acid administratedig exhibited significant promoting bile secretion. Author's address:1.Yichun University,Yichun 336000,China;2.Jiangxi Medical University,Nanchang 330006,China;3.The First People's Hospital of Yichun District,Yichun 336000,China

关 键 词：乌索酸 利胆作用 胆汁流量 胆红素 动物实验 

分 类 号：R259.75[医药卫生—中西医结合] R285.5[医药卫生—中医内科学]