尿β_2-微球蛋白在母乳性黄疸患儿早期肾功能损害诊断中的价值  

The value of determining the β_2-MG content in urine of the patients with breast milk jaundice in earlty renat damage.

作　　者：黄凯风[1] 江凤霞[1] 

机构地区：[1]广东珠海中山大学附属第五医院儿科,519000

出　　处：《中国优生与遗传杂志》2003年第4期21-22,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的　探讨尿 β2 -微球蛋白 (β2 -MG)检测在母乳性黄疸早期肾功能损害诊断中的价值。方法　对 87例母乳性黄疸患儿 ,采用放射免疫法 ,测定其尿 β2 -MG的含量 ,并对结果与正常新生儿进行对比分析。结果　母乳性黄疸患儿胆红素越高 ,尿 β2 -MG的值也越高 ,肾功能损害存在的可能性也越大。结论　尿 β2 -MG检测可作为母乳性黄疸早期肾功能损害的检测方法 ;对母乳性黄疸早期肾功能损害的诊断有一定临床价值。Objective:To explore the value of the β 2-MG content in urine of the patients with breast milk jaundice in carily ronal damage Methods: Using radioimmunoassary(RIA) mothod,were determined the β 2-MG content in nrine of the 87 patients with breast milk jaundice and 53 normal infants.Result:It showed that the higher serum total bilirubin levels,the higher β 2-MG content in urine(r=0.471,P<0.001)When the serum total bilirubin>205.2μ mol/L,the β 2-MG content of breast milk jaundice was difference than that of normal infants (P<0.01); when the serum total bilirubin≤205.2μmol/L,was not significantly different(P>0.05).Conclusion:The β 2-MG content in urine can be seen as a diagnosite index for the patients with breast milk jaundice in canly renal damage,also can help for diagnostiting the earily renal damage of the patients with breast milk jaundice.

关 键 词：母乳性黄疸 Β2-微球蛋白 肾损害 

分 类 号：R725.7[医药卫生—儿科]