血液透析佐治糖尿病高渗昏迷的研究  

Study of hemodialysis on insensible diabetics with high osmotic pressure

作　　者：李政[1] 姚红[1] 管金艳[1] 赵永智[1] 刘颖[1] 

机构地区：[1]辽宁省普兰店市第一人民医院,辽宁普兰店116200

出　　处：《现代中西医结合杂志》2003年第17期1812-1813,共2页Modern Journal of Integrated Traditional Chinese and Western Medicine

基　　金：大连市卫生局科研项目 (2 0 0 1 1 1 5)

摘　　要：目的　研究血液透析佐治糖尿病高渗昏迷的价值。方法　将 1999年 1月— 2 0 0 3年 2月在我院住院的糖尿病高渗昏迷患者随机分为 2组 :治疗组采用一般疗法 +血液透析 ,对照组采用一般疗法。观察两组患者入院时及治疗后 6 ,2 4及 36h血尿素氮、血糖、血钠、血钾及血浆晶体渗透压的变化 ;观察患者的清醒时间及不良反应等。结果　治疗后 6h治疗组各指标明显低于对照组 ;治疗后 2 4h ,除血糖外 ,治疗组各指标也低于对照组 ;治疗后 36h ,除血浆渗透压治疗组低于对照组 (P <0 .0 5 )外 ,余各项指标均不存在显著性差异 (P >0 .0 5 )。在抢救成功率、降低死亡率、存活者清醒时间方面 ,治疗组优于对照组 (P <0 .0 5 )。Objective It is to evaluate the adjuvant effect of hemodialysis on insensible diabetics with high osmotic pressure. Methods Insensible diabetics with high osmotic pressure who stayed in hospital from Jan. 1999 to Feb. 2003 were randomized into two groups. The treatment group were treated with general method and hemodialysis. The control group were treated with general method. The changes of carbamide nitrogen, sugar, Na +, K + in plasma and plasma crystal osmotic pressure were observed before treatment and 6, 24, 36 hours after treatment. Results The differences between blood bio-chemical indexes of the two groups 6 hours after treatment were significant (P<0.05). 24 hours after treatment, the indexes of treatment group except blood sugar were lower than those of control group (P<0.05). 36 hours after treatment, no obvious difference between two groups was found (P>0.05) except plasma osmotic pressure (P<0.05). Salvage successful rate, reducing death rate and the patients’ conscious time of the treatment group were more effective than those of the control group (P<0.05). Conclusion Hemodialysis is one of the effective means to insensible diabetics with high osmotic pressure.

关 键 词：血液透析 糖尿病高渗昏迷 并发症 血浆晶体渗透压 治疗 

分 类 号：R587.2[医药卫生—内分泌] R459.5[医药卫生—内科学]