复方栝楼胶囊对兔血脂、氧化修饰低密度脂蛋白和脂质过氧化作用的影响  

The lnfluence of Trichosanthes Kirilowii compound capsule on blood-lipids,oxLDL and the lipid peroxidized

作　　者：杨莉[1] 申虹[1] 杨萍[1] 刘隽[1] 桂兴芬[1] 吕翠田[2] 

机构地区：[1]河南职工医学院,郑州450003 [2]河南中医学院,郑州450003

出　　处：《中国卫生检验杂志》2003年第4期421-422,共2页Chinese Journal of Health Laboratory Technology

摘　　要：〔目的〕研究复方栝楼胶囊对兔血脂 ,oxLDL、SOD和MDA的影响。〔方法〕采用高脂饮食饲喂法建立家兔HLP(高脂血症 )模型 ,测定各实验组兔血清中oxLDL、MDA、TG、TC、HDL -C、LDL -C的含量和SOD活性。〔结果〕复方栝楼胶囊 (大、小剂量 )组SOD活性升高 ,MDA、oxLDL和LDL -C下降 ,与模型组比较有显著差异。〔结论〕复方栝楼胶囊能提高机体抗氧化能力 ,抑制脂质过氧化反应及LDL的氧化修饰。ObjectiveTo study the influence of trichosanthes kirilowii compound capsule on oxLDL, SOD and MDA in Rabbit-serum.〔Methods〕Set HLP model of Rabbit by high-lipid diet,to measure the content of oxLDL, MDA, TG, TC, HDL-C, LDL-C and activity of SOD in Rabbit-serum of each experiment group.〔Results〕As compared with the model,it has remarkable difference that the activity of SOD,has rised,the content of MDA, oxLDL and LDL-C has reduced in the trichosanthes kirilowii kompound capsule. 〔Conclusion〕trichosanthes kirilowii compound capsule can raise the antioxidated activity of the body, restrain the lipids peroxidized and LDL’S oxidated and modified.

关 键 词：复方栝楼胶囊 兔 血脂 氧化修饰低密度脂蛋白 脂质过氧化 氧自由基 高脂血症 

分 类 号：R259.892[医药卫生—中西医结合] R286.2[医药卫生—中医内科学]