尼麦角林治疗急性脑梗死40例  

Nicergoline in treatment of 40 cases of acute cerebral infarction(ACI)

作　　者：宋德林[1] 徐旭日[1] 孙润泽 钟广文[3] 

机构地区：[1]山东省青岛市市立医院,青岛266011 [2]青岛市青岛纺织医院,青岛266000 [3]海军401医院,青岛266071

出　　处：《中国新药杂志》2003年第7期559-561,共3页Chinese Journal of New Drugs

摘　　要：目的 :评价尼麦角林治疗急性脑梗死的疗效。方法 :将 80例急性脑梗死患者随机分为治疗组及对照组 ,治疗组先采用注射剂尼麦角林 8mg加入生理氯化钠溶液 2 5 0mL ,静脉滴注 ,qd ,10d为 1疗程。以后改为口服尼麦角林片 ,每次 10mg ,tid。对照组按常规治疗。 2组均观察 1个月以上。 结果 :治疗组治疗后神经功能缺损评分减少值显著高于对照组 (P <0 0 0 1) ,总有效率和治疗后日常生活活动量表评分亦显著高于对照组 (P <0 0 5～0 0 0 1)。结论 :尼麦角林能减轻急性脑梗死患者神经功能缺损 ,提高患者独立生活能力 ,有明显的脑保护作用。Objective:To study the efficacy of nicergoline in treatment of ACI.Methods:40 patients were randomly divided into nicergoline group and control group.In nicergoline group,patients were given once daily infusion of nicergoline injection 8mg diluted with 250mL of saline solution for 10d,then changed to oral nicergoline 10mg 3 times daily.In control group,patients were given routine treatment.Results:The nerve function failure grade in the nicergoline group is significantly higher than those of the control group (P<0.001).The total effective rate (P<0.05) and ADL grade (P<0.001) are obviously higher in the nicergoline group.Conclusion:The nerve function failure grade can be relieved by nicergoline treatment in ACI patients,and their independent viability is also improved.

关 键 词：尼麦角林 治疗 脑梗死 

分 类 号：R972.4[医药卫生—药品]