糖尿病眼病患者血清LPO含量变化及临床意义  

CHANGES OF SERUM LIPID PEROXIDES LEVELS AND THEIR CLINICAL VALUE

作　　者：陈佩筠[1] 何岳文[2] 芦惠霞[2] 

机构地区：[1]南京铁道医学院附属医院内分泌科 [2]南京铁道医学院附属医院检验科

出　　处：《南京铁道医学院学报》1992年第4期230-232,共3页Journal of Nanjing Railway Medical College

摘　　要：采用 TBA 荧光法测定了110例糖尿病人的血清 LPO 含量,并与50名正常对照比较。结果证实,糖尿病人血清 LPO 含量升高,P<0.01,其中以糖尿病眼病患者最为显著,眼病愈重,血清 LPO 升高亦愈明显、但糖尿病视网膜病变与糖尿病白内障患者的血清 LFO 升高程度并无差别,P>0.05。提示,糖尿病眼病患者体内氧自由基产生和清除失衡、脂质过氧化反应增强是糖尿病眼病早发、高发、快发的危险因素之一。The serum lipid peroxides(LPO)levels in 110 diabetic patients and 50 normal individuals were determined by means of TBA flurocolor imetry.The results confirmed the increase in LPO in diabetic patients(P<0.01)and a more marked change was found in those with ophthalmopathy.The more severe ophthalomopathy is,the more obvious the change in serum LPO.There was not a difference between the changes in LPO of diabetic patients with retinal lesions and those with cataract.The production and the clearence of lipid peroxidation and the strenghthening of LPO are suggested to be the risk factors for an early,rapid development and a high incidence of ophth- almopathy in diabetic patients.

关 键 词：糖尿病 白内障 视网膜疾病 LPO 

分 类 号：R587.1[医药卫生—内分泌]