使用PVA微粒为栓塞剂的部分性脾栓塞术  

Partial Splenic Embolization Using PVA Particles as Embolic Agent

作　　者：曾庆乐[1] 李彦豪[1] 陈勇 赵剑波[1] 梅雀林[1] 

机构地区：[1]第一军医大学南方医院介入治疗科,广州510515

出　　处：《临床放射学杂志》2003年第8期698-700,共3页Journal of Clinical Radiology

摘　　要：目的 评价以聚乙烯泡沫醇(PVA)颗粒为栓塞剂行部分性脾栓塞术的疗效及并发症。资料与方法 17例脾大患者以PVA颗粒为栓塞剂行部分性脾栓塞(PSE),并以同期明胶海绵颗粒为栓塞剂的19例对照,观察两者疗效及并发症发生情况。结果 PSE栓塞前及栓塞后PVA组与明胶海绵组两组间比较,白细胞计数(WBC)及血小板计数(PLT)无明显差异。PVA组栓塞部位分布均匀率为88.2％,明胶海绵组分布均匀率为31.6％。副反应主要为发热和腹痛。PVA组2例发生脾巨大囊状液化,1例发生反应性胸膜炎。结论 PVA颗粒及明胶海绵颗粒均可作为PSE的栓塞剂而取得较好疗效,但PVA微粒栓塞时分布更加合理。Objective To assess the efficacy and complication of partial splenic embolization (PSE) by using polyvinyl alcohol (PVA) particles as embolie agent. Materials and Methods PSE by using PVA particles (PVA group) and by using Gelfoam particles (Gelfoam group) was performed in 17 and 19 patients with splenomegaly, respectively. The therapeutic efficacy and complications in two groups were compared. Results Significant difference between pre- and post-operative WBC and PLT counts was found in both groups. No significant difference in WBC and PLT counts, both pre- and post-operative, existed between PVA group and Gelfoam group. The homogeneous distribution rate of embolization region in PVA group and Gelfoam group was 88.2% and 31 .6% , respectively. Fever and abdominal pain were the main side effects after the procedure. Huge cystic liquefaction of the spleen ( n = 2) and reactive pleuritis ( n = 1) were seen in PVA group. Conclusion Both PVA particles and Gelfoam particles can be used as embolie agents in PSE with good results, however, PVA particles renders a more homogeneous and rational distribution of embolization areas.

关 键 词：聚乙烯泡沫醇颗粒 栓塞剂 脾栓塞术 疗效 并发症 

分 类 号：R815[医药卫生—放射医学]