心衰康煎液对大鼠心室肌细胞动作电位影响的观察  

The Effects of the Xinshuaikang Decoction on AP of Ventricular Cells in Rats

作　　者：李建东[1] 陈彦静[1] 李永民[2] 常宝[3] 

机构地区：[1]张家口医学院生理教研室,075000 [2]张家口医学院中医系,075000 [3]张家口医学院动物管理科,075000

出　　处：《张家口医学院学报》2003年第3期10-11,共2页

摘　　要：目的 :为了观察心衰康煎液对大鼠心室肌细胞动作电位的影响。方法 :利用细胞内微电极记录技术 ,观察了 16例大鼠心室肌细胞动作电位用药前后的特征。结果 :心衰康煎液可以明显延长刺激引起动作电位的潜伏期及明显缩短动作电位时程。结论 :心衰康煎液对心肌细胞电活动有明显影响。Objective:To study the effects of the xinshuaikang decoction on AP of ventricular cells in rats .Methods:Intracellular microelectrode record technology was applied to observe the characters of AP of ventricular cells in 16 rats before and after taking drug.Results: Xinshuaikang decoction could prolong the latent period of AP induced by electrical stimulation and shorten the APD Jignificantly . Conclusion: Xinshuaikang decoction had an significant effect on the electrical activity of myocardial cells.

关 键 词：心衰康煎液 大鼠 心室肌细胞 动作电位 临床观察 中药 心衰 

分 类 号：R259.416[医药卫生—中西医结合] R286.2[医药卫生—中医内科学]