广枣对肾缺血再灌注损伤的保护作用研究  

Study of protective function of Scabiosae from renal ischemia-reperfusion injury

作　　者：张振涛[1] 吴仁奇[1] 张威[2] 张娟[3] 

机构地区：[1]内蒙古医学院,内蒙古呼和浩特010059 [2]河北省保定市第一中医院,河北保定071000 [3]中国人民解放军第252医院,河北保定071000

出　　处：《现代中西医结合杂志》2003年第18期1942-1943,共2页Modern Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的　探讨广枣对急性肾缺血再灌注损伤的肾脏的保护作用。方法　通过建立大鼠急性肾缺血再灌注损伤模型 ,观察广枣对肾缺血再灌注后血中丙二醛 (MDA)、超氧化物歧化酶 (SOD)以及肾组织Na+ ,K+ -ATP酶和Ca2 + -ATP酶活性的影响。结果　使用广枣后 ,MDA明显下降 ,SOD ,Na+ ,K+ -ATP酶和Ca2 + -ATP酶活性显著上升。Objective It is to investigate the protective func tion of Scabiosae on kidney against acute ischemia-reperfusion injury. Methods The renal ischemia-re perfusion models were established. The effect of Scabiosae on MDA, SOD in blood and Na +, K +-ATP ase , Ca 2+ -ATP ase in renal tissue were measu red. Results The conte nt of MDA decreased obviously and the contents of SOD, Na +, K +-ATP ase , Ca 2+ -ATP ase increased significantly. Conclusion Sca biosae can protect kidney from ischemia-reperfusion injury.

关 键 词：广枣 肾缺血 再灌注损伤 肾保护 丙二醛 超氧化物歧化酶 

分 类 号：R277.52[医药卫生—中医学] R282.71