莫旺综合征:1例报道及文献复习  

Morvan's syndrome:One case report and literature review

作　　者：吴恒趋[1] 李建萍[1] 张瑛[1] 

机构地区：[1]上海交通大学医学院附属仁济医院神经内科,上海200127

出　　处：《神经病学与神经康复学杂志》2016年第3期168-172,共5页Journal of Neurology and Neurorehabilitation

摘　　要：本文报道了1例莫旺综合征(Morvan's syndrome)成年患者的临床诊治过程。该患者男性,75岁,主要临床表现为肢体肌肉颤搐和无力、多汗、睡眠障碍、幻视等;辅助检查提示胸腺恶性病变可能;外周血抗电压门控钾通道(voltage-gated potassmm channel,VGKC)抗体等免疫学指标异常。在明确诊断为莫旺综合征后,该例患者接受了对症支持治疗,症状得以部分缓解。This paper reports the diagnosis and management of a 65-year-old male patient with Morvan's syndrome presenting with neurological symptoms including myokymia,myasthenia,hyperhidrosis,sleeping disorder and visual hallucination.Diagnostic examination revealed probable malignant lesion of the thymus gland,and the abnormality in immunologic function including positive expression of peripheral blood anti-voltage-gated potassium channel antibodies.This patient was definitely diagnosed of Morvan's syndrome and reached clinical partial recovery after symptomatic and supportive treatment.

关 键 词：莫旺综合征 运动失调 钾通道 电压门控 抗电压门控钾通道抗体 

分 类 号：R593.2[医药卫生—内科学]