中医药对胰岛素抵抗相关信号通路影响的研究进展  

Research Progress of TCM on Signaling Pathways Related to Insulin Resistance

作　　者：林玉芳[1,2] 韩薇[1,2] 李寅[2] 童秋瑜[2] 沈卫东[2] 

机构地区：[1]上海中医药大学研究生院,上海201203 [2]上海中医药大学附属曙光医院针灸科,上海201203

出　　处：《上海中医药大学学报》2015年第5期98-101,共4页Academic Journal of Shanghai University of Traditional Chinese Medicine

基　　金：上海市科委科研计划基金资助项目(12401903204)

摘　　要：探讨中医药对胰岛素抵抗相关信号通路影响的研究进展,主要包括对PI3K/AKT信号通路、NF-κB信号通路、GLUT4信号通路、AMPK信号通路的影响。不同的信号通路既有各自的特点,又有一定的相关性,中医药或针灸对相关信号通路的调节效果明显,对改善胰岛素抵抗提供了新的治疗措施。This paper summarizes TCM on signaling pathways of insulin resistance,which include the effects of TCM on PI3 K / AKT signaling pathway,NF-κB signaling pathway,GLUT4 signaling pathway and AMPK signaling pathway. Different signaling pathways have their own characteristics,and at the same time have certain correlations. Some signal pathways can be significantly regulated by traditional Chinese medicine or acupuncture and this offers new directions for improving insulin resistance.

关 键 词：2型糖尿病 胰岛素抵抗 信号通路 中医药疗法 针灸 

分 类 号：R285[医药卫生—中药学]