磺化-β-环糊精及手性冠醚在毛细管电泳手性拆分中的应用  

Sulfonated-β-cyclodextrins and chiral crown ether as chiral additives in capillary electrophoresis.

作　　者：冷桃花[1] 郭伟强[1] 王成云[1] 任一平 

机构地区：[1]浙江大学化学系,浙江杭州310027 [2]浙江省疾病控制预防中心,浙江杭州310009

出　　处：《浙江大学学报（理学版）》2003年第5期550-553,共4页Journal of Zhejiang University（Science Edition）

摘　　要：本文将不同取代度的水溶性磺化-β-环糊精和手性冠醚用于分离衍生后的肉碱消旋体,考察了不同取代度的环糊精作为手性添加剂的分离性能,同时研究了低取代度的环糊精与手性冠醚的联合作用机理.The water soluble sulfated- β - cyclodextrins with different degree of substitution and chiral crown ether were used as chiral selectors to separate carnitine. The effects of sulfated- β- cyclodextrins with different degree of substitution on the enantiomeric separation were investigated. The mechanism of enantioseparation using sulfated- β - cyclodextrins with low degree of substitution and chiral crown ether was also investigated.

关 键 词：毛细管电泳 手性拆分 磺化-β-环糊精 手性冠醚 肉碱消旋体 分离性能 手性添加剂 

分 类 号：O658.9[理学—分析化学] O636.12[理学—化学]