藤本豆豆荚总黄酮抗肿瘤活性的实验研究  

Research on the Anti-tumor Activity of Total Flavonoids from Perennial Lablab sp. Hull

作　　者：曹柏营[1] 戚颖欣[1] 姜秀娟[1] 昌友权[1] 

机构地区：[1]吉林工程技术师范学院食品工程学院,吉林长春130052

出　　处：《现代食品》2016年第15期117-118,共2页Modern Food

基　　金：吉林省教育厅十二五科技规划项目(编号:吉教科合字2013第369号)

摘　　要：本文通过体外和体内试验评价藤本豆豆荚总黄酮的抗肿瘤活性。藤本豆豆荚总黄酮可在体外抑制HL-60、Hep G2、BGC-823和S180肿瘤细胞的增殖,其抑制率分别为32.52%、43.13%、62.34%和74.31%,藤本豆豆荚总黄酮对小鼠体内S180肉瘤的生长存在一定的抑制作用,抑瘤率最高为59.15%。The effect of total flavonoids from Perennial Lablab sp. Hull(FPLH) on the anti-tumor activity and immunological activity were studied in vivo and vitro. The results showed that FPLH can inhibit the proliferative of cancer cells such as HL-60,Hep G2,BGC-823 and S180,the inhibition rate was 32.52%,43.13%,62.34% and 74.31% respectively. FPLH showed significant inhibitory effects on S180 tumorbearing mice,the tumor growth inhibition rate were 59.15%.

关 键 词：藤本豆豆荚 黄酮类化合物 抗肿瘤活性 

分 类 号：TS201.2[轻工技术与工程—食品科学]