小分子化合物在离子阱质谱中的分子离子反应研究  

Study on the Ion/Molecule Reactions of Low-Mass Compounds in the Ion Trap Mass Spectrometre

作　　者：陈国强[1] 郭寅龙[1] 

机构地区：[1]中国科学院上海有机化学研究所,上海200032

出　　处：《有机化学》2003年第9期977-983,共7页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金 (No.2 0 1 750 34)资助项目

摘　　要：利用离子阱质谱的原理和特点 ,研究了小分子醇、醚、胺、醛、酮等有机化合物 (分子量小于 2 0 0 )在离子阱里的分子离子反应 ,总结了反应特点和规律 ,并把它归类为自身化学电离 (SCI)反应 .以丁酮、丙烯醇为例 ,采用FTMS对反应产物离子进行准确质量测定 ,验证了它们各自的分子离子反应结果 .另外 ,把该类化合物 (30个 )SCI反应的质谱图与NIST98库中的标准EI质谱图进行了比较 ,建立了SCI质谱图库 ,提高了在离子阱质谱上对这类小分子化合物定性分析的准确率 .The ion/molecule reactions of low-mass compounds in the ion trap MS, such as alcohol, ether, amine, aldehyde, ketone and so on, were studied. The reaction characters and disciplinarians were summarized, which were described as self-chemical ionization (SCI) reactions. The products of the ion/molecule reactions of butanone and propenol were determined by FTMS. And the accurate masses of the product ions of butanone and propenol. resulting from the ion/molecule reactions were obtained. The SCI spectra were compared with the standard EI spectra (NIST98), and the database of the SCI-MS was established. Therefore the identifications of these species of low-mass compounds on the ion trap MS can be made more accurate.

关 键 词：小分子化合物 离子阱质谱 分子离子反应 有机反应机理 自身化学电离 

分 类 号：O657.63[理学—分析化学]