羟基卟啉衍生物的电喷雾多级串联质谱研究  

Electrospray Ionization Tandem Mass Spectrometry of Some Tetraphenyl-porphyrin Derivatives Containing Hydroxyl Group

作　　者：马丽[1] 黄锦汪[1] 姚骏骅[1] 罗海英[1] 范丽芬[1] 计亮年[1] 

机构地区：[1]中山大学化学与化学工程学院光电材料与技术国家重点实验室

出　　处：《分析测试学报》2003年第5期23-25,共3页Journal of Instrumental Analysis

基　　金：国家自然科学基金资助项目(20071034);广东省自然科学基金资助项目(021726)

摘　　要：研究了3种单羟基卟啉的电喷雾多级串联质谱,对其可能的裂解途径进行了归纳;结果表明,仅仅在苯环上无取代基的卟啉HPTPP中才能观察到失去活性的羟基或羟苯基的裂解碎片,苯环具有拉电子取代基的卟啉比具有推电子取代基的卟啉更容易裂解;由此可见,苯环上取代基性质对羟基卟啉的裂解方式有一定的影响。The electrospray ionzation tandem mass spectrometry of three tetraphenylporphyrin derivatives containing hydroxyl group have been investigated.The proposed fragmentation pathways have been summarized.The results indicated that the fragments with the loss of active hydroxyl group or hydroxylphenyl group were observed only in the fragmentation pathway of HPTPP and the fragmentation of the porphyrin with electron-withdrawing substituents at phenyl group is easier than that of the porphyrin electron-donating substituents at phenyl group.It seems that the substituents at phenyl group in porphyrins have some effects on their fragmentation.

关 键 词：羟基卟啉衍生物 多级串联质谱 电喷雾离子化 羟基活性 裂解途径 

分 类 号：O626.13[理学—有机化学] O657.63[理学—化学]