消化性溃疡的病因和药物治疗  

Etiologic factor and treatment of peptic ulcer disease

作　　者：沈玉根 刘建成 陈士葆[2] 

机构地区：[1]青浦区金泽镇卫生院,上海201718 [2]中国人民解放军第二军医大学长征医院消化内科,上海200003

出　　处：《中国新药与临床杂志》2003年第10期620-624,共5页Chinese Journal of New Drugs and Clinical Remedies

摘　　要：消化性溃疡是我国人群中常见病之一 ,各种因素如幽门螺杆菌感染、药物、遗传及社会心理因素等均可诱发或促进本病的发生。组胺H2 受体拮抗剂如法莫替丁、尼扎替丁等和质子泵抑制剂如奥美拉唑、兰索拉唑等抗酸分泌药物与胃粘膜保护剂如硫糖铝混悬液、胶态次枸椽酸铋等联合应用可有效的治疗消化性溃疡病。应用奥美拉唑、阿莫西林及克拉霉素三联The peptic ulcer (PU) disease is one of the common diseases in our country popul ation. Multiple factors, such as Helicobacter pylori (Hp) infection, drugs, heridity and society-psychologic factor can induce and / or promote the occurr ence of PU disease. H 2-receptor antagonist drugs (famotidine, nizatidine) and proton pump inhibitors (PPI) (omeprazole, lansoprazole) conbined with gastric m ucosa protective drugs (sucralfate, bismuth subcitrate) are effective in treatin g peptic ulcer. One triple therapy with omeprazole, amoxycillin and clarithromyc in for 7 d is highly effective in eradicating Hp and healing peptic ulcers.

关 键 词：奥美拉唑 幽门螺杆菌 消化性溃疡 药物疗法 

分 类 号：R975.6[医药卫生—药品] R573.1[医药卫生—药学]