穿心莲的提取工艺研究  

Study on Extraction Process of Andrographis Paniculata

作　　者：张玲[1] 尚立霞[1] 单卫华[1] 胡庆文[1] 时延增[1] 郭承军[1] 

机构地区：[1]山东省生物药物研究院,山东济南250014

出　　处：《时珍国医国药》2003年第8期458-460,共3页Lishizhen Medicine and Materia Medica Research

摘　　要：目的 :筛选穿心莲最佳提取工艺条件。方法 :以穿心莲内酯和脱水穿心莲内酯为检测指标 ,考察不同工艺条件对二者含量的影响。结果 :以醇提工艺提取内酯成分含量较高 ,其中 ,醇浸渍工艺 >醇渗漉工艺 >醇温浸工艺 >醇回流工艺。结论 :制备穿心莲固体制剂 ,可采用 6 5 %及 5 5 %乙醇温浸工艺 ,对于穿心莲液体制剂 ,以 6 5 %及 75 %乙醇浸渍工艺及5 5Objective:To optimize the extraction process of Andrographis paniculata.Methods:To study the factors that affect the different extraction process of Andrographis paniculata. Andrographolide and dehydroandrographolide are used as markers, and determined by TLC-scanning.Results:The alcohol extraction process is better and in which maceration>percolation>warm-infusion>reflux.Conclusion:It indicates that the 65% and 55% alcohol warm-infusion are suitable for solid medicine of Andrographis paniculata, and for liquid medicine, 65%,75% alcohol maceration and 55% alcohol-percolation are more suitable.

关 键 词：穿心莲 穿心莲内酯 脱水穿心莲内酯 提取工艺 薄层扫描 

分 类 号：R284.2[医药卫生—中药学]