志贺菌耐药分析  

Analysis of Antimicrobial Resistance of Shigella Spp

作　　者：陈群[1] 王兴 张燕 

机构地区：[1]扬州大学医学院形态学教研室,江苏省扬州市225001 [2]扬州大学第一临床医院感染科

出　　处：《医学理论与实践》2003年第8期878-879,共2页The Journal of Medical Theory and Practice

摘　　要：目的:了解1993～2001年间志贺菌菌群分布和耐药性。方法:菌种鉴定采用常规方法,药敏试验采用WHO推荐K-B纸片扩散法。结果:本地区志贺菌仍以福氏志贺菌为主,该菌对氯霉素、氨苄青霉素耐药率较高,对氟喹诺酮耐药性在上升,对头孢类抗生索耐药性较低。结论:根据药敏试验和耐药性分析合理应用抗生素。氟喹诺酮、三代头孢菌素为首选。Objective:To probe into the serotypes and drug-resistance of ShigeUa spp from 1993 to 2001 .Method:The antimicrobial susceptibilities were investigated by K-B method. The strains of Shigella were identified by the routine methods. Results: 489 strains were Shigellae flexneri, 13strains were S.sonnei,2 stains were S. boyddi. The drug tolerance rates of ampicillin and chloram-phenicol were higher than that of others, the drug tolerance rates of quinolones raised every year, but the drug tolerance rate of cephalosporins were low. Conclusion: The drug tolerance of Shigella being studied is very helpful to rational use of the antimicrobials. Quinolones and third generation of cephalosporins should be used firstly in treatment.

关 键 词：志贺菌 耐药性 菌群分布 药敏试验 抗生素 

分 类 号：R378.25[医药卫生—病原生物学] R978.1[医药卫生—基础医学]