FeCl_3比色法测定枸橼酸钾溶液的含量  

Determination of potassium citrate solution by FeCl_3 colorimetry

作　　者：林玉洪[1] 华剑[1] 

机构地区：[1]蚌埠医学院附属医院药剂科,蚌埠233004

出　　处：《安徽医药》2003年第4期293-294,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：目的　建立一种枸橼酸钾溶液的含量测定方法。方法　根据枸橼酸钾具有 2 羟基 1 羧酸结构 ,与FeCl3 络合显黄色 ,具有紫外吸收的特点 ,采用FeCl3 比色法测定枸橼酸钾含量。结果　枸橼酸钾在 0 5 170～ 2 5 85mg·L-1(r=0 9999)范围内 ,吸收度与浓度呈良好的线性关系。平均回收率 10 1 0 % ,RSD为 1 16 % (n =6 )。结论　方法稳定、简便易行、快速准确 。AIM To establish a method for the determination of potassium citrate solution. METHODS The content of potassium citrate in potassium citrate solution can be determined by FeCl 3 colorimetry based on the 2 hydroxy 1 carboxy in skeleon. could be conjugated with FeCl 3. which implied absorption move to 371 nm. RESULTS The calibration curves is linear in the range of 0 5170～2% 585 mg·L -1 ( r = 0 999 9 ) for potassium citrate. The average recovery was 101 0% with RSD of 1 16% ( n =6). CONCLUSION The method is feasible, fast and accurate and can be used for quality control of pharmacy.

关 键 词：FeCl3比色法 含量测定 枸橼酸钾溶液 质量控制 

分 类 号：R927.2[医药卫生—药学]