维拉帕米、硝苯吡啶和粉防己碱增强竹节人参镇痛作用的实验研究  

Analgesia Effect of Panax Japonicus Extract Potentated by Verapamil, Nifedipine and Tetrandrine

作　　者：刘家兰[1] 李德清[1] 段先宇[1] 

机构地区：[1]湖北民族学院医学院实验中心,湖北恩施445000

出　　处：《湖北民族学院学报（医学版）》2003年第3期21-23,共3页Journal of Hubei Minzu University(Medical Edition)

摘　　要：目的　观察竹节人参提取物与维拉帕米 (Ver)、硝苯吡啶 (Nif)、粉防己碱 (Tet)合用后镇痛作用增强及其中枢性镇痛作用 ;方法　取昆明种小鼠 ,采用热板法、扭体法及侧脑室注射法 (icv)给药 ,观察小鼠疼痛阈值改变 ;结果　竹节人参提取物与Ver、Nif、Tet合用后其镇痛作用明显增强。icv 30mg给药 ,竹节人参提取物具有显著镇痛作用 。Objective To observe the potentated effect of Panax Japonicus Extract complicated with Ver, Nif and Tet and its central analgesia. Methods Mice pain threshold value was observed using hot-plate methods, writhing methods and ICV. Result Analgesia effect of Panax Japonicus Extract is strengthened complicated with Ver, Nif and Tet. Panax Japonicus extract has obvious analgesia.

关 键 词：竹节人参提取物 维拉帕米 硝苯吡啶 粉防己碱 镇痛作用 增强作用 实验研究 

分 类 号：R285.5[医药卫生—中药学]