Medlab在神经干动作电位及传导速度测定实验中的应用  

Application of Medlab bio-signal operating system to measuring action potential of nerve cord and its velocity of conduction

作　　者：缪利英[1] 彭炜瑛[1] 亢晓冬[1] 

机构地区：[1]杭州师范学院医学院机能实验室,浙江杭州310012

出　　处：《杭州医学高等专科学校学报》2002年第3期68-70,共3页Journal of Hangzhou Medical College

摘　　要：目的　探讨Medleb信号处理系统在神经干动作电位及传导速度测定实验中的应用优势。方法　用Medleb信号处理系统测定 6只蟾蜍坐骨神经干动作电位的阈刺激 (Vth)、最大刺激 (Vmax)、双相动作电位第一相幅度 (AB1P)、单相动作电位幅度 (Amap)、双相动作电位第二相幅度 (AB2P)、双相动作电位第一相时程(DB1P)、双相动作电位第二相时程 (DB2P)、传导速度 (V)。结果　蟾蜍坐骨神经的Vth均值为 0 .5 8V ,Vmax均值为 1 4 8V ,V均值为 36 85m/s。末梢端神经干动作电位幅度、时程均小于中枢端 ,1%普鲁卡因处理神经干 ,神经冲动传导被阻断。结论　利用Medlab信号处理系统测定蟾蜍坐骨神经干动作电位方法简便 ,结果可靠 。Objective To explore the dominance of application of medlab bio-siganl operating system to measuring action potential of nerve cord and its velocity of conduction.Method MedLab software was employed to measure 9 indexes of 6 toads' sciatic nerve cord: voltage of threshold stimulus (Vth), voltage of maximal stimulus (Vmax), amplitude of biphasic action potential's first phase(AB1P), amplitude of monophasic action potential (Amap), amplitude of biphasic action potential's second phase (AB2P), duration of biphasic action potential's first phase (D1P), duration of biphase action potential's second phase (D2P), velocity of conduction (V).Results Mean Vth of toads was 0.46V, Vmax was 0.82V and V was 41m/s. Both the amplitude and duration of action potential on the twig end were less than those on the center end. The conduction of nerve impulse was interdicted by 1% procaine.Conclusion It's convenient to measure action potential of toads' sciatic nerve cord with MedLab bio-signal operating system, and the results are reliable.

关 键 词：Medlab信号处理系统 坐骨神经 动作电位 蟾蜍 

分 类 号：R338[医药卫生—人体生理学]