肾病综合征并特发性急性肾功能衰竭32例临床分析  

Clinical analysis of 32 cases with PNS combined with ARF

作　　者：李冬虹[1] 许平辉[1] 余文辉[2] 肖再雄[1] 吴琼玉[3] 

机构地区：[1]汕头大学医学院第二附属医院,广东汕头515041 [2]广东省汕头市第二人民医院,广东汕头515031 [3]广东省潮州市庵埠华侨医院,广东潮州515638

出　　处：《河北医学》2003年第8期717-719,共3页Hebei Medicine

摘　　要：目的 :总结肾病综合征并特发性急性肾功能衰竭的诊断及治疗方法。方法 :回顾性分析32例原发性肾病综合征 (primarynephroticsyndrome ,PNS)并急性肾功能衰竭 (ARF)病人的临床资料。结果 :原发性肾病综合征在病情中突然发生少尿或无尿 ,肾功能急骤恶化 ,血尿素氮及肌酐上升 ,排除继发性肾小球疾病及其他原因引起的急性肾小管坏死、急性间质性肾炎和双肾静脉主干血栓形成 ,经甲基强的松龙 (MP)和环磷酰胺 (CTX )或吗替麦考酚酯 (MMF)及标准疗程泼尼松、血液透析等对症治疗 ,32例患者肾功能均改善。结论 :PNS并特发性ARF是一种可逆性肾损害 ,如果能够及时诊断并作合理治疗 。Objective: To summarize the diagnosis and therapy of PNS combined with ARF. Methods: Retrospective analysis of the clinical data of 32 patients suffering PNS combined with ARF.Results: 32 patients with PNS suffered from acute oliguria or anuria,acute deterioration of renal function and rising of serum BUN and SCr, excluding secondly glomerular disease and acute tubular necrosis (ATN)?acute interstitial nephritis or thrombus formation of kidney trunk vein caused by other reasons. The renal function of all these patients was improved after treating with MP and CTX or MMF and normal period of cortisone treatment or hemodialysis.Conclusion : PNS combined with idiopathic ARF is a reversible renal impairment.if diagnosised in time and with reasonable treatment,the renal function can usually improve.

关 键 词：肾病综合征 急性肾衰 甲基强的松龙 环磷酰胺 吗替麦考酚酯 

分 类 号：R692[医药卫生—泌尿科学]