不同基质配比对青辛速释贴质量的影响  

Effect of different proportion of matrix on quality of Qingxin Sushi Tie

作　　者：郑国燊[1] 罗光亮 彭荣珍[1] 

机构地区：[1]暨南大学医学院第六附属医院江门市五邑中医院,广东江门529031 [2]深圳市福田区中医院,广东深圳518034

出　　处：《中草药》2003年第9期797-799,共3页Chinese Traditional and Herbal Drugs

基　　金：广东省中医药管理局立项课题 ( 0 996 2 8)

摘　　要：目的　选择以明胶、西黄蓍胶、甘油、聚丙烯酸钠和青黛制备青辛速释贴的最佳基质配比。方法　应用正交试验法 ,分别以粘度、软硬度、清凉感和刺痛感为衡量指标 ,综合评定不同基质配比下青辛速释贴的质量。结果　青辛速释贴的最佳基质配比为明胶∶西黄蓍胶∶甘油∶聚丙烯酸钠∶青黛 (8.0∶ 3 .5∶ 2 0∶ 1.3∶ 3 .0 )。Object To select the optimum proportion of matrix f or the preparation process of Qingxin Sushi Tie (QST) by gelatia, gum tragacanth , glycerol, sodium acylate and Qingdai. Methods The process was studied by orthogonal test with visco sity, soft and hard measurement algefacient sentation, twinge sentation as detec tive marker. The quality of QST was comprehensively compared by the different pr oportion of matrix. Results The optimum proportion of matrix in QST was gelatia-gum tyagacanth-glycerol-sodium acylate-Qindai (8 0∶3 5∶ 20∶1 3∶3 0). Conclusion According to the optimum proportio n of matrix in QST, the QST with better quality can be prepared.

关 键 词：青辛速释贴 基质 正交试验 

分 类 号：R283.6[医药卫生—中药学]