成年人体重10年变化与血压关系的探讨  

The Relationship Between Blood Pressure and Weight Change in Adult(10 years follow up)

作　　者：邵也常[1] 邓木兰[1] 刘小清[1] 麦劲壮[1] 石美玲[1] 饶栩栩[1] 高向民[1] 吴勇[1] 郭成业[1] 连子斌[1] 

机构地区：[1]广东省心血管病研究所,广东广州510100

出　　处：《高血压杂志》2003年第5期476-478,共3页Chinese Journal of Hypertension

基　　金：国家"八五"科技攻关基金资助项目 ( 85- 91 5- 0 1 )

摘　　要：目的　对成年人体重 10年间的动态变化及其它因素与血压关系的探讨 ,进一步阐明体重对血压的影响。方法采用整群抽样的方法 ,在 1983 -1984年对调查人群进行心血管病及心肺疾病危险因素的基线调查 ,于 1993 -1994年对队列人群再次进行随访调查 ,共调查男性 2 0 83人、女性 2 576人。结果　无论男女 ,10年后体重、BMI、收缩压、舒张压均值都比 10年前高 (P <0 0 1) ;体重的不同变化对血压的影响不同 ,体重增加组收缩压 ,舒张压增加均值大于体重不变及体重减轻组 ,差异有极显著性 ,体重不变及体重减轻组之间收缩压 ,舒张压增加均值无明显差异 ;在控制年龄后 ,偏相关分析结果显示基线体重 (BMI)、随访体重 (BMI)、体重 (BMI)变化均与收缩压、舒张压水平呈正相关 ;多元逐步回归分析结果显示 ,对收缩压有影响的自变量是年龄、家族史、随访体重、随访BMI ,对舒张压有影响的自变量则是家族史、年龄、随访体重、随访BMI和基线BMI。结论　体重的增长与血压升高关系密切 ,采取有效方式控制体重的增长是防止血压升高的重要手段之一。Objective To survey the relationship between blood pressure and weight change in ten years in adults, to explore the role of body weight in the blood pressure. Methods A prospective study was conducted among 2083 males and 2576 females in the ten years. At the baseline survey in 1983 to 1984 and follow up in 1993 to 1994, the risk of cardiovascular disease were inquired. Results The average of weight, BMI, SBP and DBP were higher in this cohort of people than ten years ago ( P <0 001). The persons whose weight increased have higher blood pressure than those with weight reduction or keep weight constant. The blood pressure have no difference in persons who weight reduction or keep weight constant. Blood pressure was correlated with weight, BMI, weight(BMI) change in ten years and hypertension family history for both males and females. After adjustment for age, positive association between blood pressure and weight, BMI, weight(BMI) change were still found. Stepwise regression analysis shows the impact of factors such as age, family history, weight, and BMI on the level of BP is significant. Conclusion Control weight rise is one of the important means to prevent increasing blood pressure.

关 键 词：血压 体重变化 流行病学 队列研究 

分 类 号：R181.3[医药卫生—流行病学]