氟伐他汀治疗高脂血症的临床疗效观察  

Clinical observation of effect of flavastatin on the treatment of hyperlipemia

作　　者：杜孟华[1] 王桂英[1] 孙明亮[1] 王荣喜[1] 

机构地区：[1]山东省德州市人民医院心内科,253000

出　　处：《实用诊断与治疗杂志》2003年第6期450-451,共2页Journal of Practical Diagnosis and Therapy

摘　　要：目的:比较氟伐他汀与辛伐他汀对高血脂的疗效。方法:60例高脂血症患者随机分为两组,氟伐他汀组30例,氟伐他汀20mg,1次/d。辛伐他汀组30例,辛伐他汀20mg,1次/d,疗程均为4周。结果:两组患者治疗后TC、TG、LDL-C下降,HDLC升高;组间无差别(P>0.05);两组均无明显不良反应。结论:氟伐他汀与辛伐他汀疗效相似,均为安全,疗效好的降脂药物。Objective To compare effects of simvastatin and fluvastatin on the treatment of hyperlipemia. Methods Sixty patients with hyperlipemia were randomly divided into two groups, as fluvastatin group and simvastatin group. The former included 30 patients who took 20mg fluvastatin once a day, and the latter included 30 patients who took 20mg simvastatin once a day. Both groups received one therapeutic course of 4 weeks. Results Both groups were decreased TC,TG,LDL-C, and increased HDL-C after treatment . There was no difference between two groups ( P > 0. 05). No side - effect was found. Conclusion Effect of fluvastatin is similar to that of simvastatin. Both are safe and effective for hyperlipemia.

关 键 词：氟伐他汀 高脂血症 治疗 疗效比较 降血脂药物 

分 类 号：R589.2[医药卫生—内分泌]