经皮腔内冠状动脉成形术对急性心肌梗死患者左心室功能的影响  

Contribution of PTCA to the improvement of left ventricular function after myocardial infarction

作　　者：李爱国[1] 尤乃祯[1] 傅绪杰[1] 刘建平[1] 李晓燕[1] 刘现亮[1] 魏敏[1] 刘科卫[1] 

机构地区：[1]济南军区总医院心血管内科,山东济南250031

出　　处：《心脏杂志》2003年第5期449-451,共3页Chinese Heart Journal

摘　　要：目的 :评价延迟的经皮腔内冠状动脉成形术 (PTCA)对急性心肌梗死 (AMI)患者左心室功能恢复的影响。方法 :6 3例初次 Q波型 AMI患者 ,于发病 2～ 3周内分别进行 PTCA治疗。全部病例梗死相关血管均为完全或次全闭塞病变。经过左心室造影计算左室射血分数 (L VEF)。梗死区室壁运动百分率及 Cortina室壁运动不良积分。PT-CA术 6个月后所有患者重复进行左心室造影及重复以上指标的测量。结果 :在 PTCA术 6个月后 ,本组病例表现出左室局部及整体收缩功能明显改善 ,PTCA前后 L VEF(5 8± 11) % vs(5 1± 10 ) % ,P<0 .0 1;梗死区室壁运动百分率 (14± 6 ) % vs(12± 6 ) % ,P<0 .0 5。Cortina室壁运动不良积分下降 (8± 4 )分 vs(10± 4 )分 ,P<0 .0 1。结论 :Q波型 AMI患者接受延迟的AIM:To assess the effect of late revascularization by primary perculaneous transluminal coronary angioplasty (PTCA) on left ventricular function of patients with acute myocardial infarction(AMI). METHODS:PTCA were performed in 63 AMI patients with initial Q-wave within 2～3 weeks after myocardial infarction. The infarct-related artery was totally or subtotally occluded in each patient. Left ventricular ejection fraction (LVEF), percent regional wall motion of infarcted wall and cortina dysfunction score were measured by left ventriculography. The above measurements and left ventriculography were performed again 6 months after PTCA. RESULTS: 6 months after PTCA, the patients showd a significant improvement in LVEF (58±11)% vs (51±10)%, P <0.01, and percent regional wall motion of infarcted wall (14±6)% vs (12±6)%, P <0.05. The cortina dysfunction score was reduced signtificantly (8±4) vs (10±4), ( P <0.01). CONCLUSION: In initial Q-wave myocardial infarction even with late reperfusion, PTCA had beneficial effects on left ventricular function.

关 键 词：心肌梗塞 血管成形术 心室功能 左 

分 类 号：R541.4[医药卫生—心血管疾病]