豆蔻挥发油β-环糊精包含工艺研究  

Study on preparation of β-cyclodextrin inclusion compound of volatile oil from Fructus Amomi Rotundus

作　　者：汤道权[1] 鲁茜[1] 王杰[1] 

机构地区：[1]徐州医学院药学系,江苏徐州221002

出　　处：《中成药》2003年第10期785-787,共3页Chinese Traditional Patent Medicine

摘　　要：目的 :研究豆蔻挥发油 β环糊精包合的最佳工艺。 方法 :正交试验法 ,考察挥发油利用率指标。结果 :优选出包合工艺为 :豆蔻挥发油 :β环糊精 1∶8,包合温度 5 0 °C ,包合时间 2h ,挥发油利用率为 79.7%。结论 :此工艺适合大生产。Objective: To study optimum inclusion process conditions for volatile oil from Fructus Amomi Rotunds. Methods: The study was carried out with orthogonal design. The process conditions were studied by determining the utilazision ratio of volatile oil from Fructus Amomi Rotundus. Results: The optimum preparation conditions for inclusion were established as: volatile oil:β CD was 1∶8, The inclusion temperature was at 50 °C and inclusion time for 2h, The ultilizasion ratio of volatile oil was 79.7%. Conclusion: The method can be used for mass production.

关 键 词：豆蔻挥发油 Β环糊精包合物 正交设计法 

分 类 号：R944.1[医药卫生—药剂学]