部分脾动脉栓塞术治疗外伤性脾破裂的实验研究与临床应用  

Experimental study and clinical utilization of partial splenic embolization in treating traumatic spleen rupture

作　　者：丁敏[1] 王毓璈[1] 陈虎[2] 倪有娣[1] 王艳芳[1] 江素君[1] 

机构地区：[1]杭州师范学院医学院外科教研室,浙江杭州310012 [2]杭州市第一人民医院放射科,浙江杭州310006

出　　处：《杭州医学高等专科学校学报》2003年第5期219-221,共3页Journal of Hangzhou Medical College

摘　　要：目的　探讨部分脾动脉栓塞术 (PSE)对外伤性脾破裂的止血效果及栓塞后脾组织再生过程。方法　对2 0只外伤性脾破裂实验兔模型成功施行PSE并对其脾组织再生进行观察。对 2例Gall和Scheele分类Ⅱ级的外伤性脾破裂患者行PSE并随访。结果　实验提示PSE止血效果好 (平均止血时间 12 8.3s) ,术后 16周左右脾组织可通过再生恢复到术前水平 ;临床观察显示PSE对 2例患者均有效止血 ,操作简单 ,创伤小 ,无明显并发症。结论　PSE能达到治疗外伤性脾破裂 ,同时还能最大限度地保存脾组织 ,是一种较好的保脾方法。Objective To investigate the effects of partial splenic embolization (PSE) on the stanching effect and spleen tissue regenerating process in the ones with traumatic spleen rupture. Methods 20 rabbit experimental models with traumatic spleen rupture were performed PSE and stanching effect and process of spleen tissue regeneration were observed. 2 patients with traumatic spleen rupture (Gall and Scheele classification:2) were treated by PSE and follow\|up survey were performed. Results The result of the experiment showed that the PSE's stanching effect was perfect (the mean time of the stanching was 128.34 seconds). The spleen tissue could regenerate to the normal level on the 16th week after the operation. Clinical observation showed that the PSE had a effective stanching in 2 patients who suffer from traumatic spleen rupture (Gall and Scheele classification:1～2). Manipulation of this technique was simple, lesion was small, and there was no complication. Conclusion PSE can not only treat traumatic spleen rupture but also preserve the spleen tissue as much as possible. It is a good method of preserving the spleen.

关 键 词：外伤性脾破裂 动脉栓塞术 部分性 止血术 

分 类 号：R657.62[医药卫生—外科学]