巨大淋巴结增生的病理改变及免疫组化研究  

STUDY ON MORPHOLOGY OF GIANT LYMPH NODES HYPERPLASIA WITH IMMUNOHISTOCHEMICAL METHOD

作　　者：袁而恩[1] 周庚寅[1] 乔柏生[1] 李素英[1] 

机构地区：[1]山东医科大学病理解剖学教研室

出　　处：《山东医科大学学报》1992年第1期32-34,共3页Acta Academiae Medicinae Shandong

摘　　要：巨大淋巴结增生16例中透明血管型14例,浆细胞型2例。前者主要病变为淋巴滤泡增大,滤泡中央及滤泡间血管明显增生且呈玻璃样变性。后者可在淋巴滤泡间见大量成熟浆细胞。甲基绿-派若宁染色结果15例呈阳性或弱阳性。PAP免疫组化染色结果15例λ·κ呈阳性。1例仅λ阳性,证实为多克隆性。认为该病是感染引起的炎症性疾病,预后良好。Sixteen cases or giant lymph nodes hyperplasia were studied with immunohistochemical and methyl green-Pyronin staining,in which there were 14 cases of hyaline-vascular type and 2 plasma-cell type.The changes in hyaline-vascular lesions were characterised by small hyaline-vascular follicles and interfollicular capillary proliferation.The plasma-cell lesions were charac-terised by follicles with intervening sheets of plasma cells.The results demon-strated that the giant lymph nodes hyperplasia were composed of multiple clone populations of lymphocyte with light chain immunopositive cells.These clinical signs and other data presented appear to favour an infectious or in-flammatory etiology.All the lesions have behaved in a benign fashion,and complete surgical excision has been curative.

关 键 词：免疫组织化学 淋巴结增生 

分 类 号：R551.202[医药卫生—血液循环系统疾病]