肾穿刺的病理分析及免疫学模式探讨  

PATHOLOGICAL ANALYSIS AND IMMUNOLOGICAL MODE IN RENAL BIOPSIES

作　　者：周庚寅[1] 刘洪琪[1] 王少军[2] 宋伟涛[3] 李盛梅[1] 谭燕泉[1] 李素英[4] 王培荣[5] 王学梅[5] 张仲秀 

机构地区：[1]山东医科大学病理解剖学教研室 [2]山东医科大学山东省卫生防疫站 [3]山东省卫生防疫站 [4]山东医科大学 [5]山东医科大学附属医院

出　　处：《山东医科大学学报》1992年第2期126-128,共3页Acta Academiae Medicinae Shandong

摘　　要：用光学、免疫荧光及透射电子显微镜对72例肾炎患者进行了肾穿刺的前瞻性研究。结果发现肾小球毛细血管丛系膜细胞不同程度的增生;用电镜观察,见上皮细胞足突融合是多数肾炎的非特异性病理特征。在相同病因和机理支配下产生的沉积物既可以是线型的,也可以是颗粒状的。因此,免疫荧光线型沉积不仅是在抗基底膜型肾小球肾炎中出现,而且可在其他型的肾小球肾炎中查见。Seventy-two cases of glomerulonephritis were observed with light,electron and immunofluorescent microscopy on the basis of renal bio-psy.The results indicated that under the same etiology and pathogenesis the deposit along the glomerular capillary loop could be either granular or linear.So that the linear deposit with immunofluorescence is not only pre-sent in anti-GBM(glomerular basement membrane)mediated glomerulone phritis but also in others.Variable mesangial cell proliferation in glome-rular tufts and foot process fusion of epithelial cell were not specific pathological features.

关 键 词：肾炎 显微镜检查 

分 类 号：R692.3[医药卫生—泌尿科学]