益气养阴方对小鼠白血病祖细胞及化疗药物敏感性的影响  

INFLUENCE OF REINFORCING QI AND NOURISHING YIN DRUGS ON CFU-L OF LEUKEMIA MICE AND CHEMOTHERAPY DRUGS SENSITION

作　　者：徐瑞荣[1] 顾振东[1] 黄文玉[1] 殷建林[2] 王冬梅[2] 

机构地区：[1]山东中医学院附院血液科,250011 [2]中国医学科学院血液学研究所

出　　处：《山东中医学院学报》1992年第1期51-53,共3页

摘　　要：通过测定 L_(7212)小鼠白血病祖细胞(CFU—L)集落形成率及在化疗药体外综合药敏实验基础上加用一定量中药,发现益气养阴方能降低 CFU—L 集落形成率和提高体外化疗药物的敏感性。提示此方能抑制白血病细胞和协同化疗药杀伤白血病细胞。清热解毒方也有抑制白血病细胞的作用。By measuring rate of CFU-L colony in L7212 leukemia and adding proper dosage of Chinese drugs on the basis of extraorganismal combining drug sensitive test of chemotherapy medicine,it is found that the decoction of reinforcing Qi and nourishing Yin can decrease the number of CFU-L and increase the drug sensitive rate of chemotherapy.The results show that the docoction can inhibit leukemia cells and enhance the antileukemia action of chemotherapy,the decoction of heat-clearing and detoxifying also has action on inhibiting leukemic cells.

关 键 词：益气养阴方 化疗药 白血病 

分 类 号：R285.5[医药卫生—中药学]