变应性鼻炎、哮喘与饮食能量的循证医学研究  

Evidence-based medicine of the relationship between allergic rhinitis and asthma and dietary energy

作　　者：程靖[1] 朱永湘[1] 张绮珠[1] 

机构地区：[1]广东药学院临床医学系,广州510224

出　　处：《循证医学》2003年第2期81-84,88,共5页The Journal of Evidence-Based Medicine

摘　　要：目的 评价饮食能量的干预措施在变应性鼻炎(AR)、哮喘患者的症状和检测等指标中的意义。方法 检索策略:通过CBMdisc、MEDLINE等数据库全面检索国内、外已发表的相关文献。选择标准:AR、哮喘患者以饮食能量为干预措施的随机对照试验或临床对照试验。资料收集和分析:由2位评价者按照上述检索策略收集文献,排除那些不符合选择标准要求的试验。主要对第1秒最大呼气量(FEV1)、用力肺活量(FVC)进行Meta分析。结果AR饮食能量的干预措施目前尚无文献报道,观察哮喘患者低动物性脂肪摄入的长期效应,检测FEV1、FVC经Meta分析,干预后较前分别提高23％(95％CI,14％-32％,P<0.000 1)、21％(95％CI,13％-29％,P<0.000 1)。结论 通过低能量饮食及有关的干预措施,改善哮喘患者的症状和各检测指标,有显著统计学意义,有必要开展更广泛和更深层的原因探索。Objective: To evaluate the effect of calorie control diet (CCD) on the symptom and examination in patients with allergic rhinitis (AR) and asthma. Methods: Search strategy: The Search for all the related literature in MEDLINE and CBMdisc has been made. Selection criteria: Randomized controlled trials (RCTs) or controlled clinical trials(CCTs) for CCD registers. Data collection and analysis: A quantitative Meta-analysis was carried out by two reviewers by using updated information based on inclusion and exclusion criteria from all RCTs or CCTs available. The Meta-analysis was based on FEV1、FVC. Results: After testing FEV1,FVC,an increase in efficiency has been obtained by 23% (95%CI,14%-32%, P<0.000 1)、21%(95%CI, 13%-29%, P<0.000 1) respectively, through the observation of the patients with the long term low energy diet, compared with the case before. Conclusion: Low energy diet improved the symptom and sign of the patients with asthma, and there is significant statistical difference.

关 键 词：变应性鼻炎 哮喘 饮食能量 循证医学 检测 

分 类 号：R765.2[医药卫生—耳鼻咽喉科] R562.25[医药卫生—临床医学]